Dr Astrid Olsnes KITTANG

Contact Information

Dr. Astrid Olsnes Kittang
University of Bergen, Faculty of Medicine
Address: Haukeland University Hospital, Jonas Lies vei 65, 5019 Bergen, Norway

Email: astrid.kittang@uib.no
Tel:    +4792330302

Current research interests

My current research interest is focused mainly on the pathogenesis, diagnosis and development of new treatment of clonal myeloid malignancies in adults, especially myelodysplastic syndrome (MDS). I am interested in the role of chemotaxis of various immune cells, including myeloid derived suppressor cells and the role of the bone marrow stem cell niche in the development and relapse of disease. Through collaboration with partners in the Nordic countries, I am also involved in the design of clinical trials and  care programmes for patients with acquired and hereditary bone marrow disease, as well as conducting various clinical trials at Section for Hematology, Haukeland University Hospital.

Clinical Expertise related to EuNet-INNOCHRON

Clinical Haematology with special experience in patients with chronic neutropenia and myeloid malignancies (MDS/AML). 

Laboratory Epertise related to EuNet-INNOCHRON

  • Microscopy 
  • Flow cytometry of PB and BM
  • In vitro assays/cell culture, studies of chemotaxis, immune suppression and differentiation

Recent publications related to Eunet-INNOCHRON

  • Bizymi N, Bjelica S, Kittang AO, Mojsilovic S, Velegraki M, Pontikoglou C, Roussel M, Ersvær E, Santibañez JF, Lipoldová M, Papadaki HA. Myeloid-Derived Suppressor Cells in Hematologic Diseases: Promising Biomarkers and Treatment Targets. Hemasphere. 2019 
  • Azrakhsh NA, Mensah-Glanowska P, Sand K, Kittang AO. Targeting Immune Signaling Pathways in Clonal Hematopoiesis. Curr Med Chem. 2019 
  • Sand K, Theorell J, Bruserud Ø, Bryceson YT, Kittang AO. Reduced potency of cytotoxic T lymphocytes from patients with high-risk myelodysplastic syndromes. Cancer Immunol Immunother. 2016 
  • Kittang AO, Kordasti S, Snd KE, Costantini B, Kramer AM, Perezabellan P, Seidl T, Rye KP, Hagen KM, Kulasekararaj A, Bruserud Ø, Mufti GJ. Expansion of myeloid derived suppressor cells correlates with number of T regulatory cells and disease progression in myelodysplastic syndrome. Oncoimmunology. 2015