Time flies.. The time for our EuNet-INNOCHRON 3rd Management Committee and 2nd Working Group meeting approaches (March 2-3 ,2021). We are looking forward to meeting you all and discuss the current projects and future plans of our Action.
3rd MANAGEMENT COMMITTEE MEETING and
2nd WORKING GROUPs MEETING
02-03 MARCH 2021
Virtual event via ZOOM platform
https://us02web.zoom.us/j/9102688668
TIME ZONE: Central European Time (CET)
Tuesday 2nd March 2021
MANAGEMENT COMMITTEE MEETING
14:00 - 16:00 Management Committee Meeting
(eligible for participation: MC members or designated MC substitutes and MC observers)
Wednesday 3rd March 2021
WORKING GROUPS MEETING
(eligible for participation: all EuNet-INNOCHRON participants)
10:00 - 10:15 Welcome to participants - Introduction
Helen Papadaki, Carlo Dufour
10:15 - 13:00 Updates from the Working Groups – Part I
10:15 - 11:00 Working Group 1 ‘Congenital Neutropenias’ session
Chairs: Alan Warren, Karl Welte
J. Skokowa: “Role of BAALC in leukemogenesis in SCN patients”
A. Warren: “Somatic genetic rescue of a germline ribosome assembly defect”
11:00 - 11:45 Working Group 2 ‘Acquired Neutropenias’ session
Chairs: Petter Hӧglund, Juergen Bux
Update on the progress and deliverables of WG2 (15 min)
- Training school in antibody identification in AIN (C. Dufour - F. Fioredda)
- Development of SOP on AIN techniques (J. Bux - I. Mavroudi - C. Pontikoglou)
- NGS on myeloid genes (G. Tsaknakis - H. Papadaki)
- Ongoing studies (P. Höglund)
New research data (30 min)
- G. Tsaknakis - H. Papadaki: "The clonal haemopoiesis and clonal evolution in CIN"
- P. Höglund: "The blood protein hCAP-18 in neutropenia: an 18-month experience of a new ELISA for clinical use"
11:45 - 12:30 Working Group 3 ‘Mechanisms of Leukaemic Evolution’ session
Chairs: Ivo Touw, Cristina Mecucci
P. Olofsen: "Truncated CSF3 receptors induce pro-inflammatory responses in SCN”
I. Touw: “A new genetic subtype of SCN with an autosomal dominant inheritance”
P. Olofsen: “PML-controlled responses in SCN with ELANE-misfolding mutations”
12:30 - 13:00 Break
13:00 - 14:30 Updates from the Working Groups Part II
13:00 - 13:45 Working Group 4 ‘Targets for Novel Therapies’ session
Chairs: Julia Skokowa, Joanna Cichy
J. Cichy: "Generation of a cellular model for investigating roles of elastase inhibitors in neutropenia"
J. Skokowa: Nicotinamide (vitamin B3) treatment improves response to G-CSF in SCN patients ".
J. Donadieu: “SGTL2 inhibitor in Glycogen storage disease Ιb and G6PC3”
13:45 - 14:30 Working Group 5 ‘Registries and biobanking’ session
Chairs: Jean Donadieu, Cornelia Zeidler, Kostas Stamatopoulos
J. Donadieu: “Classification of CNP”
C. Zeidler: “Registry for CNP in Europe”
K. Stamatopoulos: “Biobanking”
14:30 - 15:00 Presentation and Discussion by the Young EuNet-INNOCHRON
Maksim Klimiankou - Valentino Bezzerri
15:00 - 15:15 Break
15:15 - 17:45 Horizontal projects of the Action
15:15 - 15:45 Guidelines
Francesca Fioredda - Helen Papadaki
15:45 - 16:15 Documentation of COVID-19 infection in CN patients
Jan Palmblad - Marije Bartels - Carlo Dufour - Daniela Guardo
16:15 - 16:45 Autoimmune neutropenia cases preceding ALL
Jelena Roganovic
16:45 - 17:15 Clinical-Molecular Biology-Genetics board of experts
Julia Skokowa - Cornelia Zeidler
17:15 - 17:45 Leukaemia NGS pannel
Julia Skokowa - Hannah Tamary - Grigorios Tsaknakis
17:45 - 18:00 Summary and conclusions
Helen Papadaki, Carlo Dufour
|
Speakers/Chairs |
Affiliation |
|
|
Dr |
Juergen Bux |
Ruhr University, Bochum, Germany |
|
Dr |
Marije Bartels |
University Medical Center Utrecht, Utrecht, the Netherlands |
|
Dr |
Valentino Bezzerri |
Cystic Fibrosis Center, Azienda Ospedaliero Universitaria Ospedali Riuniti, Ancona,Italy |
|
Dr |
Joanna Cichy |
Jagiellonin University, Krakow, Poland |
|
Dr |
Jean Donadieu |
AP-HP, Trousseau Hospital, France, Paris |
|
Dr |
Carlo Dufour |
G.Gaslini Children's Research Hospital, Hematology Unit, Genova, Italy |
|
Dr |
Francesca Fioredda |
G.Gaslini Children's Research Hospital, Genova, Italy |
|
Dr |
Daniela Guardo |
IRCCS Istituto Giannina Gaslini, Genova, Italy |
|
Dr |
Petter Hӧglund |
Karolinska University Hospital, Stockholm, Sweden |
|
Dr |
Maksim Klimiankou |
University Hospital Tübingen, Tübingen, Germany. |
|
Dr |
Irene Mavroudi |
University of Crete, School of Medicine / University Hospital of Heraklion, Crete, Greece |
|
Dr |
Cristina Mecucci |
University of Perugia, Perugia, Italy |
|
Ms |
Patricia Olofsen |
Erasmus Medical Center, Rotterdam, the Netherlands |
|
Dr |
Charalampos Pontikoglou |
University of Crete, School of Medicine / University Hospital of Heraklion, Crete, Greece |
|
Dr |
Jan Palmblad |
Karolinska Institutet, Stockholm, Sweden |
|
Dr |
Helen Papadaki |
University of Crete, School of Medicine / University Hospital of Heraklion, Crete, Greece |
|
Dr |
Jelena Roganovic |
Clinical Hospital Centre Rijeka / Faculty of Medicine of the University of Rijeka, Croatia |
|
Dr |
Julia Skokowa |
University Hospital Tübingen, Tübingen, Germany |
|
Dr |
Kostas Stamatopoulos |
Institute of Applied Biosciences, Thessaloniki, Greece |
|
Dr |
Hannah Tamary |
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel / Schneider Children's Medical Center of Israel, Petach Tikva, Israel |
|
Dr |
Ivo Touw |
Erasmus Medical Center, Rotterdam, the Netherlands |
|
Dr |
Grigorios Tsaknakis |
University of Crete, School of Medicine, Heraklion, Crete, Greece |
|
Dr |
Alan Warren |
University of Cambridge, Cambridge, United Kingdom |
|
Dr |
Karl Welte |
University Children Hospital, Tübingen, Germany |
|
Dr |
Cornelia Zeidler |
Hannover Medical School/ Clinic for Hematology, Hemostaseology, Oncology and Stem Cell Transplantation, Hannover, Germany |