1. Isolated neutropenia preceding acute lymphoblastic leukemia in children. Roganovic, J., Ricci, E., Polychronopoulou, S. and Fioredda, F. (2022). Pediatr Blood Cancer e29518. https://doi.org/10.1002/pbc.29518

  2. eIF6 rebinding dynamically couples ribosome maturation and translation
    Pekka Jaako, Alexandre Faille, Shengjiang Tan, Chi C. Wong, Norberto Escudero-Urquijo, Pablo Castro-Hartmann, Penny Wright, Christine Hilcenko, David J. Adams, Alan J. Warren. bioRxiv 2021.09.06.459071; doi: https://doi.org/10.1101/2021.09.06.459071

  3. A zebrafish model for HAX1-associated congenital neutropenia. Doll L, Aghaallaei N, Dick AM, Welte K, Skokowa J, Bajoghli B. Haematologica. 2021 May 1;106(5):1311-1320. doi: 10.3324/haematol.2019.240200. PMID: 32327498; PMCID: PMC8094079.

  4. PML-controlled responses in severe congenital neutropenia with ELANE-misfolding mutations. Olofsen PA, Bosch DA, Roovers O. Blood Adv. 2021;5(3):775-786. doi:10.1182/bloodadvances.2020003214

  5. NAMPT/SIRT2-mediated inhibition of the p53-p21 signaling pathway is indispensable for maintenance and hematopoietic differentiation of human iPS cells. Xu, Y., Nasri, M., Dannenmann, B., Mir, P., Zahabi, A., Welte, K., Morishima, T., & Skokowa, J. (2021). Stem cell research & therapy, 12(1), 112. https://doi.org/10.1186/s13287-021-02144-9

  6. Secondary CNL after SAA reveals insights in leukemic transformation of bone marrow failure syndromes. Schmied, L., Olofsen, P. A., Lundberg, P., Tzankov, A., Kleber, M., Halter, J., Uhr, M., Valk, P., Touw, I. P., Passweg, J., & Drexler, B. (2020). Blood advances, 4(21), 5540–5546. https://doi.org/10.1182/bloodadvances.2020001541

  7. RUNX1 Mutations in the Leukemic Progression of Severe Congenital Neutropenia. Olofsen, P. A., & Touw, I. P. (2020). Molecules and cells, 43(2), 139–144. https://doi.org/10.14348/molcells.2020.0010

  8. CRISPR/Cas9 Genome Editing of Human-Induced Pluripotent Stem Cells Followed by Granulocytic Differentiation. Dannenmann, B., Nasri, M., Welte, K., & Skokowa, J. (2020). Methods in molecular biology (Clifton, N.J.), 2115, 471–483. https://doi.org/10.1007/978-1-0716-0290-4_27

  9. Modeling severe congenital neutropenia in induced pluripotent stem cells. Olofsen PA, Touw IP. In: Birbrair A, ed. Recent Advances in iPSC Disease Modeling, vol. 1. Chapter 5. Waltham, MA: Academic Press; 2020:85-101

  10. Recurrent bacterial infections, but not fungal infections, characterise patients with ELANE-related neutropenia: a French Severe Chronic Neutropenia Registry study
    Rotulo, G.A., Plat, G., Beaupain, B., Blanche, S., Moushous, D., Sicre de Fontbrune, F., Leblanc, T., Renard, C., Barlogis, V., Vigue, M.-G., Freycon, C., Piguet, C., Pasquet, M., Fieschi, C., Abou-Chahla, W., Gandemer, V., Rialland, F., Millot, F., Marie-Cardine, A., Paillard, C., Levy, P., Aladjidi, N., Biosse-Duplan, M., Bellanné-Chantelot, C., Donadieu, J. and (2021), Br J Haematol. https://doi.org/10.1111/bjh.17695

  11. Malignant Transformation Involving CXXC4 Mutations Identified in a Leukemic Progression Model of Severe Congenital Neutropenia.
    Patricia A. Olofsen, Szabolcs Fatrai, Paulina M.H. van Strien, Julia C. Obenauer, Hans W.J. de Looper, Remco M. Hoogenboezem, Claudia A.J. Erpelinck-Verschueren, Michael P.W.M. Vermeulen, Onno Roovers, Torsten Haferlach, Joop H. Jansen, Mehrnaz Ghazvini, Eric M.J. Bindels, Rebekka K. Schneider, Emma M. de Pater, and Ivo P. Touw, Cell Reports Medicine Volume 1, Issue 5, 100074, August 25, 2020. https://doi.org/10.1016/j.xcrm.2020.100074

  12. Complement and tissue factor-enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis
    Panagiotis Skendros, Alexandros Mitsios, Akrivi Chrysanthopoulou, Dimitrios C Mastellos, Simeon Metallidis, Petros Rafailidis, Maria Ntinopoulou, Eleni Sertaridou, Victoria Tsironidou, Christina Tsigalou, Maria G Tektonidou, Theocharis Konstantinidis, Charalampos Papagoras, Ioannis Mitroulis, Georgios Germanidis, John D Lambris, Konstantinos Ritis, J Clin Invest. 2020 Aug 6;141374. doi: 10.1172/JCI141374. Online ahead of print. (PubMed)

  13. Circumventing Mutation to Nix Neutropenia
    Skokowa J. N Engl J Med. 2021 May 20;384(20):1956-1958. doi: 10.1056/NEJMcibr2102952. PMID: 34010536

 

Under Review

Structure of the AAA-ATPase Drg1 during extraction of Rlp24 from pre-60S particles. Prattes M, Grishkovskaya I, Hodirnau V-V, Hetzmannseder C, Zisser G, Sailer C, Vasileios Kargas, Loibl M, Gerhalter M, Kofler L, Warren AJ, Stengel F, Haselbach D and Bergler H. Under review, Nature Structural and Molecular Biology