Dr. Cornelia ZEIDLER

Contact Information

Dr. Cornelia Zeidler
Severe Chronic Neutropenia International Registry (SCNIR) Europe
Address: Hannover Medical School
Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation
Carl-Neuberg-Str. 1
30625 Hannover, Germany 

Email: Zeidler.Cornelia@mh-hannover.de 
Tel:    +49 511 557105
Fax:   +49-511-557106
Url:    www.severe-chronic-neurtropenia.org
Url:    www.sds-registry-europe.org

Current research interests

I have devoted my research career to study the natural course of congenital bone marrow failure syndromes with focus on congenital neutropenias in peadiatric and adult patients, including all genetic subtypes, Kostmann, syndromeSDS, Barth syndrome and GSD 1b. My main research interests are the long-term outcome of treatment with granulocyte colony-stimulating factor (G-CSF), the identification of risk factors for the development of malignant transformation and the development of new treatment strategies for these disorders.

Clinical Expertise related to EuNet-INNOCHRON

Clinical Haematology in paediatric and adult patients with special experience in patients with all subtypes of severe chronic neutropenia and secondary leukemia.

Laboratory Epertise related to EuNet-INNOCHRON

  • Not applicable
  • Co-operation with SCNIR laboratory in Tuebingen (Prof. J. Skokowa)

Recent publications related to Eunet-INNOCHRON

  • Dale DC, Bolyard AA, Steele LA, Zeidler C, Welte K; Severe Chronic Neutropenia International Registry. Registries for study of nonmalignant hematological diseases: the example of the Severe Chronic Neutropenia International Registry. Curr Opin Hematol. 2019 Nov 19. doi: 10.1097/MOH.0000000000000558. [Epub ahead of print] PubMed PMID: 31764167.
  • Skokowa J, Dale DC, Touw IP, Zeidler C, Welte K. Severe congenital neutro-penias. Nat Rev Dis Primers. 2017 Jun 8;3:17032. doi: 10.1038/nrdp.2017.32. Review. PubMed PMID: 28593997; PubMed Central PMCID: PMC5821468.
  • Klimiankou M, Mellor-Heineke S, Klimenkova O, Reinel E, Uenalan M, Kandabarau S, Skokowa J, Welte K, Zeidler C. Two cases of cyclic neutropenia with acquired CSF3R mutations, with 1 developing AML. Blood. 2016 May 26;127(21):2638-41. doi: 10.1182/blood-2015-12-685784. Epub 2016 Mar 30. PubMed PMID: 27030388.
  • Klimiankou M, Klimenkova O, Uenalan M, Zeidler A, Mellor-Heineke S, Kandabarau S, Skokowa J, Zeidler C, Welte K. GM-CSF stimulates granulopoiesis in a congenital neutropenia patient with loss-of-function biallelic heterozygous CSF3R mutations. Blood. 2015 Oct 8;126(15):1865-7. doi: 10.1182/blood-2015-07-661264. Epub 2015 Aug 31. PubMed PMID: 26324699.
  • Makaryan V, Zeidler C, Bolyard AA, Skokowa J, Rodger E, Kelley ML, Boxer LA, Bonilla MA, Newburger PE, Shimamura A, Zhu B, Rosenberg PS, Link DC, Welte K, Dale DC. The diversity of mutations and clinical outcomes for ELANE-associated neutropenia. Curr Opin Hematol. 2015 Jan;22(1):3-11. doi:10.1097/MOH. 0000000000000105. Review. PubMed PMID: 25427142; PubMed Central PMCID: PMC4380169.
  • Zeidler C, Grote UA, Nickel A, Brand B, Carlsson G, Cortesão E, Dufour C, Duhem C, Notheis G, Papadaki HA, Tamary H, Tjønnfjord GE, Tucci F, Van Droogenbroeck J, Vermylen C, Voglova J, Xicoy B, Welte K. Outcome and management of pregnancies in severe chronic neutropenia patients by the European Branch of the Severe Chronic Neutropenia International Registry. Haematologica. 2014 Aug;99(8):1395-402. doi: 10.3324/haematol.2013.099101. Epub 2014 Jul 4. PubMed PMID: 24997149; PubMed Central PMCID: PMC4116840.