Dr Laura GRECH

Contact Information

Dr. Laura Grech
Post Doc
Univeristy of Malta
Address: Lab of Molecular Genetics, University of Malta, Msida

Email: lauragrech87@gmail.com
Tel:    +35679959025

Current research interests

My main intereset is in haemoglobin switching mainly the foetal to adult switch and its therapeutic  role in subjects with beta thalassaemia and sickle cell disease. Our main aim is to study drugs and small molecules that can elevate foetal haemoglobin in subjects with thalassaemia and sickle cell disease.

Clinical Expertise related to EuNet-INNOCHRON


Laboratory Epertise related to EuNet-INNOCHRON

  • Culture of Human erythroid progenitor cells
  • Real-time PCR
  • RNA extraction
  • cDNA synthesis
  • RNA sequencing
  • ATAC sequencing

Recent publications related to Eunet-INNOCHRON

  • Perkins, A., Xu, X., Higgs, D. R., Patrinos, G. P., Arnaud, L., Bieker, J. J......... Grech, L., ..... Philipsen, S., 2016). "Kruppeling" erythropoiesis: An unexpected broad spectrum of human red blood cell disorders due to KLF1 variants unveiled by genomic sequencing. Blood, 14,127(15): 1856-62.