Dr Sonja Pavlovic
Laboratory for Molecular Biomedicine
Institute of Molecular Genetics and Genetic Engineering
University of Belgrade
Address: Institute of Molecular Genetics and Genetic Engineering
Vojvode Stepe 444a 
11010 Belgrade 
Serbia

Email: sonya@sezampro.rs
Tel:     +381 11 3976 445

My main research interest is molecular genetics of rare diseases, including congenital neutropenias and hematological malignancies. Stem cell biology and pharmacogenomics and pharmacotranscriptomics are also in the focus of my research.

I am a molecular geneticist, with an expertise to diagnose congenital neutropenias on molecular level, to functionally characterize novel disease-causing and disease-related variants and to discover molecular pathways which elucidate the molecular basis of congenital neutropenias.

I am also involved in the study of molecular basis of adult and childhood hematological malignancies, including association studies.

• NGS (exome sequencing)
• Sanger sequencing
• Real time PCR
• Low density microarrays
• Methodology for characterization of novel variants (in silico analysis, functional analysis, CRISPR/Cas gene editing)
• Cell culture

• Skakic A, Andjelkovic M, Tosic N, Klaassen K, Djordjevic M, Pavlovic S, Stojiljkovic M. CRISPR/Cas9 genome editing of SLC37A4 gene elucidates the role of molecular markers of endoplasmic reticulum stress and apoptosis in renal involvement in glycogen storage disease type Ib. Gene.2019;703:17-25. 
• Sarajlija A, Djordjevic M, Kecman B, Skakic A, Pavlovic S, Pasic S, Stojiljkovic M. Impact of genotype on neutropenia in a large cohort of Serbian patients with glycogen storage disease type Ib. Eur J Med Genet. 2019 Sep 16:103767. doi: 10.1016/j.ejmg.2019.103767.
• Skakic A, Djordjevic M, Sarajlija A, Klaassen K, Tosic N, Kecman B, Ugrin M, Spasovski V, Pavlovic S, Stojiljkovic M. Genetic characterization of GSD I in Serbian population revealed unexpectedly high incidence of GSD Ib and 3 novel SLC37A4 variants. Clin Genet. 2018 Feb;93(2):350-355. 
• Marjanovic I, Kostic J, Stanic B, Pejanovic N, Lucic B, Karan-Djurasevic T, Janic D, Dokmanovic L, Jankovic S, Vukovic NS, Tomin D, Perisic O, Rakocevic G, Popovic M, Pavlovic S, Tosic N. Parallel targeted next generation sequencing of childhood and adult acute myeloid leukemia patients reveals uniform genomic profile of the disease. Tumour Biol. 2016;37(10):13391-401.