Prof David C. Dale

Contact Information

Prof David C. Dale
Address:Dept Medicine, Box 356422,
University of Washington, Seattle WA USA

Tel:     206-543-7215

Current research interests

I am the PI for the NIH supported Severe Chronic Neutropenia International Registry. Dr. Karl Welte and I are the Co-Directors of the SCNIR. I am interested in the patigenesis, genetic and cellular mechanisms neutropenia and treatment for these conditions 

Clinical Expertise related to EuNet-INNOCHRON

  • Hematology,
  • neutrophil disorders
  • and Internal Medicine 

Laboratory Epertise related to EuNet-INNOCHRON

  • Diagnostic testing for neutropenia 
  • Hematopoietic cell growth and proliferastion
  • Neutrophil kinetics and neutropenia

Recent publications related to Eunet-INNOCHRON

  • Dale DC, Makaryan V. ELANE-Related Neutropenia. 2002 Jun 17 [Updated 2018 Aug 23]. In: Adam MP, Ardinger HH, Pagon RA, et al., eds. GeneReviews® [Internet].): University of Washington, Seattle;
  • Makaryan V, Kelley MK, Fletcher B, Bolyard AA, Aprikyan A, Dale, DC.  Elastase inhibitors as potential therapies for ELANE-associated neutropenia. J Leukoc Biol. 2017;102(4):1143-1151. PMC5597518
  • Skokowa J, Dale DC, Touw IP, Zeidler C, Welte K. Severe congenital neutropenias. Nat Rev Dis Primers. 2017;8(3):17032. PMC5821468
  • 417. Dale DC, Bolyard AA, Marrero T, Bonilla MA, Link DC, Newburger P, Shimamura A, Boxer LA, C Spiekerman. Long-term effects of G-CSF therapy in cyclic neutropenia. N Engl J Med. 2017;377:1-2. PMC5777346