Contact Information

Prof Helen Papadaki
University of Crete, School of Medicine
Address: University of Crete, Medical School, 5D11 Wing
& University Hospital of Heraklion, 71500 Voutes, Heraklion, Crete, Greece

Tel:    +302810394637

Current research interests

My current research interest is focused mainly on the pathogenesis of chronic neutropenia in adults. I am specifically interested in the identification of cellular, molecular, immune and genetic mechanisms underlying different types of chronic neutropenias, the differential diagnosis of the benign from the pre-malignant cases and the early recognition of malignant evolution based on longitudinal follow-up of these patients. The role of the BM microenvironment in the pathogenesis of chronic neutropenia and MDS is also one of my main research interests. 

Clinical Expertise related to EuNet-INNOCHRON

Clinical Haematology with special experience in patients with chronic neutropenia and myeloid malignancies (MDS/AML). 

Laboratory Epertise related to EuNet-INNOCHRON

  • Flow cytometry of PB and BM
  • BM cultures of HSCs 
  • Studies of BM MSCs
  • Real-time PCR
  • Anti-neutrophil antibody screening usisng GAT-GIFT

Recent publications related to Eunet-INNOCHRON

  • Bizymi N, Bjelica S, Kittang AO, Mojsilovic S, Velegraki M, Pontikoglou C, Roussel M, Ersvær E, Santibañez JF, Lipoldová M, Papadaki HA. Myeloid-Derived Suppressor Cells in Hematologic Diseases: Promising Biomarkers and Treatment Targets. Hemasphere. 2019 Jan 28;3(1):e168. 

  • Bizymi N, Velegraki M, Damianaki A, Koutala H, Papadaki HA. Altered Monocyte Subsets in Patients with Chronic Idiopathic Neutropenia. J Clin Immunol. 2019 Nov;39(8):852-854.

  • Mavroudi I, Eliopoulos AG, Pontikoglou C, Pyrovolaki K, Damianaki A, Koutala H, Zervou MI, Ximeri M, Mastrodemou S, Kanellou P, Goulielmos GN, Papadaki HA. Immunoglobulin and B-cell disturbances in patients with chronic idiopathic neutropenia. Clin Immunol. 2017 Oct;183:75-81. 

  • Mastrodemou S, Stalika E, Vardi A, Gemenetzi K, Spanoudakis M, Karypidou M, Mavroudi I, Hadzidimitriou A, Stavropoulos-Giokas C, Papadaki HA, Stamatopoulos K. Cytotoxic T cells in chronic idiopathic neutropenia express restricted antigen receptors.Leuk Lymphoma. 2017 Dec;58(12):2926-2933.